I've been on greyhound buses many times, with no problems.
However, I can tell you that its definitely no way to travel if you have little kids.
Bums everywhere hanging out in the greyhound stations asking for money/food (angry, violent bums)
Low-lifes in general that ride the buses themselves, probably who got the money from killing someone and robbing them
But then again,
I live in san diego, california
and the many times i've been on greyhound it was from San Diego, going through Los Angeles, and then through Sacramento.
So those are some of the worst places to go through
